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And specifically in glaucoma, I might add. TS: But what sort of dynamic is shaping up here? Is this going to be a horse race? Is this going to be a battle for the MIGS market? And there are more to come. If you go to OIS. But I asked Dr. Rick Lewis. Rick Lewis: There is. The MIGS space has always been defined by the target tissue.
So for example, the eye stent has been directed at the canal space. Transcend has been directed at the suprachoroidal space, and AqueSys with the Zen procedure is in the subconjunctival space. And maybe the race will heat up when they begin to cross over and show that these different mechanisms can work in different spaces. But at this point, there really is very little cross over between the three?
RL: Well, at this point, at least by FDA labeling will indicate that the canal space is limited to open end glaucoma; the Zen perhaps may be restricted to more advanced disease. Will it hopefully will treat both primary and secondary glaucomas in some of the more advanced problems. I spoke to Dr. Andrew Iwach. But regarding MIGS and Transcend and all the other players, Glaukos of course, I asked him sort of how will these entities coexist, and who is likely or what is likely to help determine the winners or at least the leaders in this space.
Can we repeat it? So I think that in some patients, an iStent at the time of cataract surgery might be the excellent choice. On the other hand, the new Transcend devices also look very encouraging. But as a surgeon who uses these, boy do I love having the options. We have now a number of options. You know, we do a full history. It goes on for three days and it looks at the both existing treatments and new treatments coming down the pike.
I talked again to Dr. Singh about the event, asked him what were some of the highlights, and if he was surprised by anything presented, either early or late stage over those three days. I was pleased to see that there are several drug delivery companies that have external and internal approaches that are doing exciting work. ForSight Vision5, Ocular Therapeutics.
So for example, have external technologies that would be their Helios Ring, so ForSight, and the punctal plug approach with Ocular Therapeutics. There are also several companies looking at intraocular, intracameral or posterior segment drug delivery for glaucoma as well. TS: So we hear a lot of familiar names in that account of what he heard, what Dr. I also talked with Dr. Lewis about Glaucoma He had delivered the Fredrick Sutro Memorial Lecture, the keynote address there. And in his talk, he gave an account of the many years he has spent working with glaucoma startups, with glaucoma companies about developing new products and new treatments.
This is going on 30 years of consulting in glaucoma. Rick Lewis: Well, I had the honor of giving the Sutro Lecture, which is the main lecture of that meeting. And this was focused on my 30 years of consulting in glaucoma. And I think we have to learn from our mistakes in all aspects of this, both in drug development as well as the launching of the products.
And I pointed out a number of problems and some successes in getting clinicians to change behavior and also in helping our patients. So it was a lot of fun for me to be able to put this together. TS: Can you share one or two ugly developments for us? RL: Well, you know, one of the ones was a launch of a product. Well it was originally an Israeli company, Kolapinol that launched the Express. And they contracted with Ciba to launch it in the US.
This was about a little over ten years ago. And so in about a 5 to minute session, you were able to take your device, which had an injector, inject a few into a pig eye, and then they gave you a — printed out a certification.
So people went home and felt they were experts in glaucoma surgery. And it led to the — they pulled the device off the market, and had to relaunch it in a different way. It took a couple years to relaunch it. Ultimately, the Express turned out to be a good device, and Alcon acquired the Express a few years ago.
But it was an example of very, very nearsighted approach to launching a clinical product. The reverse of that, I think, was what Glaukos did with the iStent, with how they very carefully selected surgeons who were very, very competent. They actually sent many of them to Armenia to do additional training off site.
They had their reps well trained in the OR, had them do a certain number of cases under direct supervision before they were given the green light to go. And very important lesson that was learned. So again, I could have talked for hours about some of the things that happened here. Of course, he again created and leads Glaucoma I asked him the question that I asked Drs. But the question I asked to the three, and Dr. Circular Economy and Value Chains.
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WebALCON has a total of 37 patent applications. Its first patent ever was published in It filed its patents most often in Poland, China and United States. Its main competitors in its . WebJul 31, · July 31, By. Press Releases. (PRESS RELEASE) Alcon, the global leader in eye care dedicated to helping people see brilliantly, announced that the world . WebJan 6, · Alcon's (ALC) Surgical franchise continues to lead the market with its portfolio of advanced technology, intraocular lenses, a substantial installed base of equipment .